hei oc1 cells (MedChemExpress)
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Hei Oc1 Cells, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 4576 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hei+oc1+cells/Cell+Counting+Kit-8/pm41698483-84-10-17
Average 99 stars, based on 4576 article reviews
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CCK-8 Assay:Article Title: Pharmacological activation of GPX4 by selenomethionine attenuates cisplatin-induced ototoxicity and hearing loss. Article Snippet: Cisplatin, an extensively used and effective antineoplastic agent for treating various malignancies, is well known for its ototoxicity.. However, clinical treatments for ototoxicity remain limited.. In this study, we investigated the protective role of selenomethionine (SeMet), an organic selenium compound, against cisplatin-induced ototoxicity. Incubation:Article Title: Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling. Article Snippet: Mitochondrial dysfunction, which is the primary mechanism underlying cisplatin-induced hearing loss, can potentially be mitigated by modulating the redox balance and reprogramming the energy metabolism to remodel mitochondrial homeostasis.. Herein, N-acetyl-l-cysteine–derived carbonized polymer dots (NAC CPDs) are embedded into manganese porphyrin–doped metal–organic frameworks and encapsulated using a polydopamine (PDA) coating and gelatin methacryloyl (GelMA) hydrogel to afford functionalized nanozyme microcapsules.. Owing to their injectability and adhesion properties, these microcapsules exhibit the advantages of prolonged retention in the middle ear and sustained release in the inner ear. Staining:Article Title: Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling. Article Snippet: Mitochondrial dysfunction, which is the primary mechanism underlying cisplatin-induced hearing loss, can potentially be mitigated by modulating the redox balance and reprogramming the energy metabolism to remodel mitochondrial homeostasis.. Herein, N-acetyl-l-cysteine–derived carbonized polymer dots (NAC CPDs) are embedded into manganese porphyrin–doped metal–organic frameworks and encapsulated using a polydopamine (PDA) coating and gelatin methacryloyl (GelMA) hydrogel to afford functionalized nanozyme microcapsules.. Owing to their injectability and adhesion properties, these microcapsules exhibit the advantages of prolonged retention in the middle ear and sustained release in the inner ear. Knock-Out:Article Title: Loss of RAD6B induces degeneration of the cochlea in mice. Article Snippet: Presbycusis is a form of age-related hearing loss (AHL).. Many studies have shown that the degeneration of various structures in the cochlea of the inner ear is related to AHL, and DNA damage is an important factor leading to the above process.. As an E2 ubiquitin-conjugated enzyme, RAD6B plays an important role in DNA damage repair (DDR) through histone ubiquitination. Expressing:Article Title: IL-1β promotes glutamate excitotoxicity: indications for the link between inflammatory and synaptic vesicle cycle in Ménière’s disease Article Snippet: HEI-OC1 cells were cultured in high‐glucose Dulbecco’s modified Eagle medium (DMEM; Gibco, Grand Island, NE, USA) with 10% fetal bovine serum (Gibco) at 33 °C in a humidified incubator containing 10% CO2. .. In the experiments, |
